acute respiratory failure low hematocrit and hemoglobin

Polycythemia contributes to the development of cor pulmonale and pulmonary hypertension, which are linked to poor prognosis. As hypoxia promotes erythropoiesis, COPD has long been recognized as an important cause of secondary polycythemia. Hemoglobin (Hb) abnormalities, including anemia and polycythemia, are common in the COPD population. In 2020, COPD is projected to rank fifth worldwide in terms of disease burden and third in terms of mortality. In this group of patients, attention should be paid to those with high Hb levels.Ĭhronic obstructive pulmonary disease (COPD) is characterized by chronic airflow limitation, inflammation and lung remodeling. High Hb is associated with an increased risk of in-hospital death in COPD patients with CKD, especially among those with advanced CKD. Hb > 14 g/dL was related to an increased risk of death in advanced CKD patients (OR, 4.579 (95% CI, 1.243–16.866)). CKD and advanced CKD were defined as estimated glomerular filtration rates 17 g/dL was associated with an increased risk of death in the CKD group with an odds ratio (OR) of 2.085 (95% CI, 1.019–4.264). The average Hb level during hospitalization was used as the Hb level. A total of 47,209 patients who presented with COPD between January 2012 and December 2016 were included. This retrospective study was multicenter population-based. This study aimed to investigate the relationship between high Hb and in-hospital mortality and to explore reference Hb intervals in patients with COPD and CKD. Although high hemoglobin (Hb) is detrimental to CKD patients, its relationship with poor outcomes in the COPD population has not been reported. Chronic kidney disease (CKD) is a common comorbidity of chronic obstructive pulmonary disease (COPD).

Acute respiratory failure low hematocrit and hemoglobin